Bulletin of the American Physical Society
2018 Annual Meeting of the APS Mid-Atlantic Section
Volume 63, Number 20
Friday–Sunday, November 9–11, 2018; College Park, Maryland
Session B01: Poster Session (Day 1)
8:00 PM,
Friday, November 9, 2018
Edward St. John
Room: Lounge
Chair: Wendell T. Hill, III, University of Maryland, College Park
Abstract ID: BAPS.2018.MAS.B01.29
Abstract: B01.00029 : Developing new experimental techniques to understand neuronal networks*
Presenter:
Samira Aghayee
(University of Maryland, College Park)
Authors:
Samira Aghayee
(University of Maryland, College Park)
Patrcik Kanold
(University of Maryland, College Park, MD, United States)
Wolfgang Losert
(Univ of Maryland-College Park)
All optical manipulation and read out of neuronal activity has provided new opportunities for investigating neuronal network dynamics in real time. However there exists technical issues that need to be overcome to allow these techniques to reach their potential. To correct for the persistent jitter that is present in in-vivo recordings we introduced a particle-tracking based motion correction algorithm that is fast enough for realtime motion compensation. The speckles and non-uniform existing in holographic illumination prevents reliable targeting of neurons. To address this problem and to preserve the optical accessibility of the FOV we use a non-conventional optical configuration that implements a virtual lens. Finally, to over come the limited time resolution induced by the refreshing rate of the spatial light modulator, we implement a fast switching holographic technique that is capable of targeting different neurons on relevant timescales to activity propagation.
*Supported by BRAIN initiative grant U01NS090569 (PK, WL) and University of Maryland Seed Support.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.MAS.B01.29
Follow Us |
Engage
Become an APS Member |
My APS
Renew Membership |
Information for |
About APSThe American Physical Society (APS) is a non-profit membership organization working to advance the knowledge of physics. |
© 2024 American Physical Society
| All rights reserved | Terms of Use
| Contact Us
Headquarters
1 Physics Ellipse, College Park, MD 20740-3844
(301) 209-3200
Editorial Office
100 Motor Pkwy, Suite 110, Hauppauge, NY 11788
(631) 591-4000
Office of Public Affairs
529 14th St NW, Suite 1050, Washington, D.C. 20045-2001
(202) 662-8700