Bulletin of the American Physical Society
APS March Meeting 2021
Volume 66, Number 1
Monday–Friday, March 15–19, 2021; Virtual; Time Zone: Central Daylight Time, USA
Session R01: Learning without Neurons
8:00 AM–11:00 AM,
Thursday, March 18, 2021
Sponsoring Unit: DBIO
Chair: Arvind Murugan, University of Chicago
Abstract: R01.00003 : Prediction and learning in immune repertoires
9:12 AM–9:48 AM
Living systems often attempt to predict the future state of the environment based on the learned statistics of past environments. Given the stochastic nature of many biological systems how is that possible? I will show that even a system as complicated as the immune system has reproducible outcomes. Yet predicting the future state of a complex environment requires weighing the trust in new observations against prior experiences. In this light, I will present a view of the adaptive immune system as a dynamic Bayesian machinery that updates its memory repertoire by balancing evidence from new pathogen encounters against past experience of infection to predict and prepare for future threats.
The American Physical Society (APS) is a non-profit membership organization working to advance the knowledge of physics.
1 Physics Ellipse, College Park, MD 20740-3844
Editorial Office 1 Research Road, Ridge, NY 11961-2701 (631) 591-4000
Office of Public Affairs 529 14th St NW, Suite 1050, Washington, D.C. 20045-2001 (202) 662-8700