Bulletin of the American Physical Society
APS March Meeting 2019
Volume 64, Number 2
Monday–Friday, March 4–8, 2019; Boston, Massachusetts
Session K65: Phase Separation in Biological Systems
8:00 AM–10:48 AM,
Wednesday, March 6, 2019
BCEC
Room: 260
Sponsoring
Units:
DBIO DPOLY GSNP GSOFT
Chair: Jean-Charles Walter, Université de Montpellier
Abstract: K65.00013 : The role of motility in Myxococcus xanthus droplet formation and droplet geometries*
10:24 AM–10:36 AM
Presenter:
Cassidy Yang
(Princeton University)
Authors:
Cassidy Yang
(Princeton University)
Katherine Copenhagen
(Princeton University)
Joshua Shaevitz
(Princeton University)
surfaces when starved to form 3D droplet-like aggregates known as fruiting bodies consisting of hundreds
of thousands of cells. Active self-propulsive forces of individual bacteria generate local increased
pressures that drive the dewetting process. Unlike passive fluids that form axisymmetric spherical cap-
shaped droplets, these aggregates are symmetry breaking and are often elongated in an elliptic-like
shape. To examine the role of motility in dewetting, we present here the dynamics of both stable and
unstable droplet geometries during dewetting and the formation of these fruiting bodies for cells with
different Peclet numbers. Using sparsely labelled cells, we also track emergent collective flows within
these droplets to characterize the internal hydrodynamics and cellular organization.
*This work was supported by the following: NSF-PHY-1401506, NSF PHY-1521553, NSF PHY-1734030, and the NSF GRFP
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