Bulletin of the American Physical Society
APS March Meeting 2018
Volume 63, Number 1
Monday–Friday, March 5–9, 2018; Los Angeles, California
Session E49: Evolutionary and Ecological Dynamics - I
8:00 AM–11:00 AM,
Tuesday, March 6, 2018
LACC
Room: 511A
Sponsoring
Units:
DBIO GSNP
Chair: Minsu Kim, Emory University
Abstract ID: BAPS.2018.MAR.E49.3
Abstract: E49.00003 : Adaptation in pushed waves*
8:48 AM–9:00 AM
Presenter:
Diana Fusco
(Physics and Integrative Biology, Univ of California - Berkeley)
Authors:
Diana Fusco
(Physics and Integrative Biology, Univ of California - Berkeley)
Oskar Hallatschek
(Physics and Integrative Biology, Univ of California - Berkeley)
Using theory and simulations, we find that introducing cooperative effects in the population, which changes the dynamics of the wave from pulled to pushed, increases the effect of selection and allows beneficial mutations to establish more readily while purging deleterious mutations. At low mutation rate, in the sequential fixation regime, strong cooperation thus leads to faster adaptation. By contrast, at high mutation rate, clonal interference dominates and the adaptation rate exhibits a non-monotonic trend as a function of cooperation.
*Funding is provided by the National Science Foundation Career Award to OD (Number 1555330).
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.MAR.E49.3
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