Study on the Physical and Biochemical Properties of Fullerene Derivatives and CNTs (Carbon Nano Tubes) for Cancer Treatment

Nanotechnology is ever more frequently the star of biochemistry as it continually unlocks methods to cure disease. Among its clinical applications, fullerenes and CNTs (Carbon Nano Tubes), as well as metal oxides, are being utilized in therapy for cancer patients. These nano-scaled compounds exhibit anti-tumor properties that inhibit cancer from spreading throughout the body, and a wide variety of fullerenes and CNTs have the potential to be applied in the therapeutic process. Once a fullerene is absorbed by one's cells, its C60 derivatives react to light radiation by transforming molecular oxygen into reactive oxygen, thereby triggering apoptosis in the HeLa cells and other cancer cells that are able to absorb such molecules. 

In this project, physical and biochemical properties of the fullerenes and CNTs as tumor cell inhibitors were studied. Also the thermodynamic stability of all the derivatives were studied in the light of their promising role in treating tumor cells. The Avogadro software was used to measure the optimization energy of each compounds. Complexes with relatively low optimization energies were predicted to be more thermodynamically stable than those with relatively high energies.