Bulletin of the American Physical Society
71st Annual Meeting of the APS Division of Fluid Dynamics
Volume 63, Number 13
Sunday–Tuesday, November 18–20, 2018; Atlanta, Georgia
Session G17: Biological fluid dynamics: Biological Pumps
10:35 AM–12:45 PM,
Monday, November 19, 2018
Georgia World Congress Center
Room: B304
Chair: Timothy Wei, University of Nebraska, Lincoln
Abstract ID: BAPS.2018.DFD.G17.9
Abstract: G17.00009 : Analysis of esophageal transport on reconstructed models from medical images*
12:19 PM–12:32 PM
Presenter:
Sourav Halder
(Theoretical and Applied Mechanics, Northwestern University)
Authors:
Sourav Halder
(Theoretical and Applied Mechanics, Northwestern University)
Shashank Acharya
(Mechanical Engineering, Northwestern University)
Wenjun Kou
(Feinberg School of Medicine, Northwestern University)
John Erik Pandolfino
(Feinberg School of Medicine, Northwestern University)
Peter J. Kahrilas
(Feinberg School of Medicine, Northwestern University)
Neelesh Ashok Patankar
(Mechanical Engineering, Northwestern University, Theoretical and Applied Mechanics, Northwestern University)
The dynamics of esophageal bolus transport involves a complex interaction between muscle activation, esophageal wall material properties and the bolus. A better understanding of the physiologic biomechanics of esophageal transport will potentially improve patient diagnosis and treatment. This is an extension of the previous work on esophageal transport based on continuum mechanics where the simulations were performed on a simple cylindrical geometry. In this work, we have developed 3D models of the esophagus from medical scan image sequences. These images can be from various sources like Magnetic Resonance Imaging (MRI) or Computed Tomography (CT) or Barium Swallow Test. This process mainly involves image segmentation to visualize the anatomy of the esophagus, generation of surface meshes and, finally, generate solid models for analysis. Immersed Boundary Finite Element method is used to develop a fully resolved model of the esophagus. Though the shape of the esophagus varies from patient to patient, this analysis gives more realistic insights of esophageal transport that could be more clinically relevant.
*This work was supported by NIH grant 5R01DK079902-09.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.DFD.G17.9
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