Bulletin of the American Physical Society
85th Annual Meeting of the APS Southeastern Section
Volume 63, Number 19
Thursday–Saturday, November 8–10, 2018; Holiday Inn at World’s Fair Park, Knoxville, Tennessee
Session J02: Soft Matter, Complex Fluids and Polymers |
Hide Abstracts |
Chair: Wei Tain, Oak Ridge National Lab Room: Holiday Inn Knoxville Downtown LeConte |
Saturday, November 10, 2018 8:30AM - 9:00AM |
J02.00001: Ultrasound-active theranostic microcapsules of antioxidant polyphenolic multilayers Invited Speaker: Eugenia Kharlampieva Despite the accessibility of ultrasound, the clinical potential of ultrasound-active theranostic agents has not been fully realized because it requires combining sufficient imaging contrast, high encapsulation efficiency and ultrasound-triggered release in one entity. This talk focuses on ultrasound-sensitive multilayer capsules as efficient contrast enhanced imaging agents. These capsules are composed of hydrogen-bonded polyphenol tannic acid and poly(N-vinylpyrrolidone) and capable of encapsulating and delivering the anticancer drug doxorubicin upon low-power (~100 mW/cm2) diagnostic or high-power (>10 W/cm2) therapeutic ultrasound irradiation. We will also discuss the capsule efficacy in modulating the redox state that can influence immune responses for prolong circulation in the blood. The ability of this material to conjugate metalloporphyrin to further enhance immunomodulatory potential by dissipation of free radicals will be also presented. Owing to the active contrast, long circulation, customizable size, shape, composition, and precise delivery of high payload concentrations, these materials present a powerful and safe platform for imaging-guided precision drug delivery. |
Saturday, November 10, 2018 9:00AM - 9:30AM |
J02.00002: Impact of Dynamics in Soft Matter on Macroscopic Response Invited Speaker: Gerald Johannes Schneider Soft materials are ubiquitous in nature and technical applications. From cell membranes to car tires, the morphology at the nanoscale and the dynamics at the time-scale from picoseconds to microseconds links to the properties of the material at the larger length-scale. Many techniques record the relaxation time over a certain window that can capture more than 10 orders of magnitude. However, often the structure is the key to understand dynamics more in detail, especially if certain correlations exist. To identify relationships neutron spectroscopy is particularly useful, due to is ability to measure a dynamic correlation function with a very high spatial resolution. Small-angle neutron-scattering and neutron spin echo spectroscopy are very powerful tools to explore the morphology and dynamics, respectively. The talk discusses those experimental results that can be obtained and how the information and the high spatial resolution can be utilized to deepen the understanding of other experimental techniques. |
Saturday, November 10, 2018 9:30AM - 10:00AM |
J02.00003: Dynamics in Highly Rigid Polymers: Solutions to Membranes Invited Speaker: Naresh C Osti Creating new materials that are capable of energy production and storage to fulfill the present day’s energy crisis is a challenging task. Advancement of energy technology can benefit greatly from the development of more efficient, higher functioning materials that have optimized properties for energy applications. Dynamics of various elements in this type of system have great influence on the system's physical properties and response when use in device configuration. Here I will present two initiatives towards understanding systems with potential for energy applications. The first study looks the dynamics at a rigid luminescent polymer (dinonyl poly-para-phenylene ethynylene (PPE)) in solution and second in a rigid ionomer (sulfonated polyphenylene(SPP)) membranes. PPEs associate spontaneously into several complex fluids in solution, where their side chains impact the association and the conformation of the backbone. As association takes place the motion of the side chain changes accordingly. It is rather surprising that the side chains remain dynamic though macroscopically the structure is frozen. On the other hand, SPP, which makes highly rigid ionic networks in membrane, are immobile but the water trapped in the membrane remains dynamic and occupy multiple sites, either bound or loosely constrained, and bounce between the two. Effect of water content and temperature on dynamics will be discussed. |
Follow Us |
Engage
Become an APS Member |
My APS
Renew Membership |
Information for |
About APSThe American Physical Society (APS) is a non-profit membership organization working to advance the knowledge of physics. |
© 2024 American Physical Society
| All rights reserved | Terms of Use
| Contact Us
Headquarters
1 Physics Ellipse, College Park, MD 20740-3844
(301) 209-3200
Editorial Office
100 Motor Pkwy, Suite 110, Hauppauge, NY 11788
(631) 591-4000
Office of Public Affairs
529 14th St NW, Suite 1050, Washington, D.C. 20045-2001
(202) 662-8700