Bulletin of the American Physical Society
APS March Meeting 2024
Monday–Friday, March 4–8, 2024; Minneapolis & Virtual
Session Z36: Plant and Fungal Physics II
11:30 AM–1:42 PM,
Friday, March 8, 2024
Room: 103B
Sponsoring
Unit:
DBIO
Chair: Jean-Francois Louf, Auburn University
Abstract: Z36.00008 : Stochastic simulations of cortical microtubule dynamics using Cytosim to derive biophysical principles of morphogenesis in Arabidopsis leaf trichomes.*
1:18 PM–1:30 PM
Presenter:
Eashan Saikia
(Sainsbury Laboratory, University of Cambridge)
Authors:
Eashan Saikia
(Sainsbury Laboratory, University of Cambridge)
francois nedelec
(Sainsbury Laboratory, University of Cambridge)
This study establishes a biophysical link between CMT-CSC dynamics and wall structure in Arabidopsis trichomes - an ideal system because they are single-celled, easily accessible, and reproducible. The organization of CMT, predicted in silico using Cytosim - a stochastic simulation suite, is meticulously compared with confocal image data obtained before and after trichome branching. Subsequently, simulation of CMT-CSC interaction enables the calculation of local CMF orientation. This comprehensive framework can be readily applied to other biological systems, and serve as an initial foundation to faithfully reproduce various functional anatomical features experimentally.
*This study has been funded by The Gatsby Charitable Foundation, The Peak, 5 Wilton Road, London, SW1V 1AP.
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