Bulletin of the American Physical Society
APS March Meeting 2024
Monday–Friday, March 4–8, 2024; Minneapolis & Virtual
Session Z27: Mechanics of Cells and Tissues IV
11:30 AM–2:30 PM,
Friday, March 8, 2024
Room: 101H
Sponsoring
Units:
DBIO DSOFT
Chair: Moumita Das, Rochester Institute of Technology
Abstract: Z27.00013 : Oral: A mathematical and computational model to study the role of the cardiac jelly during morphogenesis
1:54 PM–2:06 PM
Presenter:
Daniel Santos-Olivan
(European Molecular Biology Laboratory (EMBL))
Authors:
Daniel Santos-Olivan
(European Molecular Biology Laboratory (EMBL))
Alejandro Torres Sánchez
(European Molecular Biology Laboratory (EMBL))
In this study, we introduce a detailed mathematical model to describe the dynamics of the cardiac jelly. Our model captures the intricate interplay between its elasticity, viscosity, and time-dependent deformation. This approach allows us to look deeper into the physical properties that govern the cardiac jelly's behavior during embryonic development.
The main application of our model is to investigate fracture generation within the cardiac jelly. Using our mathematical framework and a finite element computational implementation, we simulate a 3D model of the cardiac jelly. This enables us to study the generation of fracture patterns depending on the geometrical and material properties of the system and to compare our results with experimental observations in zebrafish embryos.
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