APS March Meeting 2024
Monday–Friday, March 4–8, 2024;
Minneapolis & Virtual
Session T55: Biomaterials and Nanotechnology
11:30 AM–2:30 PM,
Thursday, March 7, 2024
Room: 204AB
Sponsoring
Units:
DBIO DSOFT
Chair: Ramakrishna Podila, Clemson University
Abstract: T55.00013 : Transition metal doped ZnO ferromagnetic nanoparticles for cancer cure
2:18 PM–2:30 PM
Abstract
Presenter:
Aurangzeb Khan
(Abdul Wali Khan University Mardan)
Author:
Aurangzeb Khan
(Abdul Wali Khan University Mardan)
This study presents the synthesis, characterization, and potential applications of these nanoparticles in the context of cancer cure. The synthesis of transition metal-doped ZnO nanoparticles involved the incorporation of transition metals, such as cobalt (Co), iron (Fe), and manganese (Mn), into the ZnO lattice. This process was meticulously controlled to ensure the uniform dispersion of dopants within the ZnO structure. The resulting nanoparticles were characterized using a variety of techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM), and vibrating sample magnetometry (VSM). These analyses confirmed the successful integration of transition metals and the generation of ferromagnetic properties within the nanoparticles. The emergence of ferromagnetism in these nanoparticles at room temperature holds significant potential for cancer cure applications. One of the key avenues explored is the use of hyperthermia, where the nanoparticles can be selectively targeted to cancer cells and exposed to an external magnetic field. This localized application of heat can induce apoptosis (cell death) in cancer cells while sparing healthy tissue, making it a highly targeted and less invasive treatment option. Moreover, the nanoparticles' magnetic properties open avenues for drug delivery systems. By functionalizing the surface of these nanoparticles, anticancer drugs can be loaded and precisely delivered to tumor sites, enhancing drug efficacy while minimizing systemic side effects. The utilization of transition metal-doped ZnO ferromagnetic nanoparticles in cancer cure strategies represents a significant advancement in the field of oncology. Their unique combination of ferromagnetic behavior, biocompatibility, and tunable properties positions them as a versatile tool for both hyperthermia-based therapies and targeted drug delivery. This research bridges the gap between materials science and medical applications, offering new possibilities for more effective and less invasive cancer treatments. As cancer remains a global health challenge, these nanoparticles hold great promise in contributing to improved patient outcomes and enhanced quality of life.