Bulletin of the American Physical Society
2024 APS March Meeting
Monday–Friday, March 4–8, 2024; Minneapolis & Virtual
Session N37: Microbial Communities II
11:30 AM–2:18 PM,
Wednesday, March 6, 2024
Room: 103C
Sponsoring
Unit:
DBIO
Chair: Arthur Prindle, Northwestern University
Abstract: N37.00009 : Rapid antibiotic susceptiblity test using white-light interferometry*
1:06 PM–1:18 PM
Presenter:
Adam J Krueger
(Georgia Institute of Technology)
Authors:
Adam J Krueger
(Georgia Institute of Technology)
Peter Yunker
(Georgia Institute of Technology)
Bikash Bogati
(Emory University)
David Weiss
(Emory University)
Our previous work uses the surface topography of a community to detect phenotypically heterogeneous populations. Now we take advantage of the coffee ring effect to develop a novel method of relative cell counting using volume from white light interferometry as a proxy for number of cells. This technique will reduce the number of doubling times required for detection. Quickly differentiating resistant phenotypes will enhance clinical treatment information which will improve antibiotic stewardship as well as treatment outcomes.
*NIH R35 GM138354
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