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Zirconium Pentatelluride (ZrTe5) is a topological material that hosts non-trivial topological phases under different stimuli, such as strain, temperature, and magnetic field. Here we report a study of the effect of uniaxial strain in ZrTe5 on the fermi surface and transport properties in magnetic fields up to 14 Tesla. The strain was applied in situ using piezoelectric stacks. We found a strain induced change in the quantum oscillations of magnetoresistivity and hall resistivity suggesting a change in the fermi surface. Specifically, we found upon compressive strain the hall resistivity sign reversal occurs progressively at lower magnetic field in comparison to the unstrained sample, consistent with the scenario of a strain and magnetic field induced Lifshitz transition.