Bulletin of the American Physical Society
APS March Meeting 2023
Volume 68, Number 3
Las Vegas, Nevada (March 5-10)
Virtual (March 20-22); Time Zone: Pacific Time
Session Z08: Evolutionary Dynamics II
11:30 AM–2:18 PM,
Friday, March 10, 2023
Room: Room 131
Sponsoring
Unit:
DBIO
Chair: Antonio Carlos Costa, Ecole Normale Superieure Paris
Abstract: Z08.00009 : Tuning spatial distributions of selection pressure to suppress emergence of resistance*
1:30 PM–1:42 PM
Presenter:
Thomas Tunstall
(University of Exeter)
Authors:
Thomas Tunstall
(University of Exeter)
Philip Madgwick
(Syngenta)
Ricardo Kanitz
(Syngenta)
Wolfram Moebius
(University of Exeter)
Motivated by the control of pests in agriculture, we employ a one-dimensional model with agents diffusing and selection applied temporarily on a sub-region only. We find that an optimal size of this sub-region exists which minimises resistance emergence per area protected. We observe that this result carries over to higher dimensions and determine analytical bounds for the location of the optimum.
We extend the results to environments consisting of equally spaced subregions that are protected temporarily. This allow us to answer how a large given region can be subdivided to optimally suppress resistance emergence. These findings are a step towards optimised protocols for pesticide application that protect crop and suppress emergence of resistance at the same time.
*Thomas Tunstall was supported by an EPSRC DTP PhD studentship and Syngenta.
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