Bulletin of the American Physical Society
APS March Meeting 2023
Volume 68, Number 3
Las Vegas, Nevada (March 5-10)
Virtual (March 20-22); Time Zone: Pacific Time
Session PP08: V: Multicellular Phenomena II
9:00 AM–11:00 AM,
Tuesday, March 21, 2023
Room: Virtual Room 8
Sponsoring
Unit:
DBIO
Chair: Dominic Alfonso, National Energy Technology Laboratory
Abstract: PP08.00007 : Optical reflection statistics from a thin weakly disordered optical media: application to detection of structural alterations in cells/tissues*
10:36 AM–10:48 AM
Presenter:
Alexander Punnoose
(City College of New York)
Authors:
Alexander Punnoose
(City College of New York)
Shirsendu Nanda
(University of Illinois at Chicago)
Prabhakar Pradhan
(Mississippi State University)
The model is applicable to analyzing the reflected light in experiments that employ the partial wave spectroscopy technique. We show how they can be directly applied to extract the cell/tissue thickness and mean sample refractive index to determine the structural disorder parameter – a key biological marker for disease-related abnormal alterations in the intracellular structures. Applications in different types of disease detection in cells/tissues are also discussed.
[1] A. Punnoose, S. Nanda, and P. Pradhan. Opt. Exp. 29, 43612-43625 (2021)
*Support from NIH R21CA260147 is acknowledged.
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