Bulletin of the American Physical Society
APS March Meeting 2023
Volume 68, Number 3
Las Vegas, Nevada (March 5-10)
Virtual (March 20-22); Time Zone: Pacific Time
Session A16: From Grains to Complex Flows to Sustainable Materials: Soft Matter Meets Climate Change
8:00 AM–11:00 AM,
Monday, March 6, 2023
Room: Room 208
Sponsoring
Units:
DSOFT GSNP
Chair: Vinutha H.A., Georgetown University
Abstract: A16.00009 : Mechanical stability of lipid monolayers and bilayers in the presence of pollutants
10:00 AM–10:12 AM
Presenter:
Marina Pasquet
(UC Berkeley)
Authors:
Marina Pasquet
(UC Berkeley)
Joelle Frechette
(UC Berkeley)
However, despite recent efforts to investigate the role of commercial beads with some pollutants on bilayers (the main component of cell membrane) the effect of PFAS and/or microplastics with complex shapes, sizes and chemical compositions on living systems is still not fully understood. To address this gap, we propose to investigate how varying proportions of real microplastics and/or PFOA/PFOS affect the dynamics and the stability of lipid monolayers and bilayers (DPhPC).
We will first quantify monolayers dynamics at a water-hexadecane interface with measurements of surface tension, using the pendant drop method. We will then characterize droplet interface bilayers (DIB), where the bilayer is formed between two drops, to study the mechanical response of bilayers in the presence of pollutants. Altogether, this work aims to advance our understanding of the role of pollution on lipid membranes, in an effort to illuminate possible fundamental causes of pollution-related damage to cells and guide future avenues of remediation research.
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