Electrospun, non-woven, nano-fibrous novel Poly(vinyl Alcohol) membranes functionalized with L-Arginine for virus capture*

The development of pretreatment membranes have led to multiple advancements in water and air filtration systems. Previous studies have tested the porous structure, tensile strength, and physicochemical properties by introducing different ligands to the backbone of a polymer. Electrospinning a membrane can lead to improvement in reproducible samples, and accuracy in pore size.One derivative of these membranes can serve as an antiviral layer in a mask rendering more accurate results with eco-friendly materials, reusability, and increased screening accuracy in viral droplets. The enhanced electronegative properties of the mat are supported by previous experiments to attract and capture viruses of multiple varieties.This electronegative property will have increased longevity compared to previously produced masks due to the electrospinning process. The nano-fibrous electrospun polyvinyl(alcohol) mat can then be functionalized with L-arginine to increase the charged guanidinium groups in the membrane. These charged groups will then improve ionic conductivity, thermal and chemical stability. The interchangeable steps of crosslinking and quaternizing the PVA come after electrospinning the solution of ligand and polymer. Crosslinking the membrane will enhance the overall tensile strength and mechanical properties.The Quaternization fabricates an anion-exchange and enhances hydrophilicity. The different concentration ratios of L-arginine to the PVA, and the variety cross linking reagents were tested with a carbon capture apparatus which supported evidence of functionalized L-arginine. The chemical shifts in H-NMR supported a physical incorporation of the L-Arginine to the surface of the polymer. However, there is no evidence of esterification that will support a chemical bonding to the surface. However, virus capture apparutus testing resulted in 100% virus capture on the control supporting improved porous structure for the PVA mat encouraging further testing.