Bulletin of the American Physical Society
APS March Meeting 2022
Volume 67, Number 3
Monday–Friday, March 14–18, 2022; Chicago
Session G04: Physics of Cell Fate Transitions II
11:30 AM–2:30 PM,
Tuesday, March 15, 2022
Room: McCormick Place W-176C
Sponsoring Unit: DBIO
Chair: Simon Freedman, Northwestern University
Abstract: G04.00013 : Competition between two cell types under cell cycle regulation with apoptosis*
2:18 PM–2:30 PM
Simon K Schnyder
Matthew S Turner
(Univ of Warwick)
We determine the coexistence line on which two colonies coexist. We find that not always does the colony with the higher characteristic pressure invade the other, but the apoptosis rate can also play a key role. Comparing the dynamics from the two initial conditions reveals the role of statistical noise and Laplace pressure. Our findings shed light on how cancer develops and draw attention to the interplay between characteristic pressure and apoptosis rate.
*This work is supported by the Grants-in-Aid for Scientific Research (JSPS KAKENHI) under Grants No. 20H00129 and 20H05619.
The American Physical Society (APS) is a non-profit membership organization working to advance the knowledge of physics.
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