Single liposome tracking in dense suspensions of stabilized liposomes

Methods developed to stabilize phospholipid vesicles against fusion, up to volume fraction around 80{\%}, enable one to perform single-particle tracking on these soft, flexible, hollow objects. Stabilization is accomplished by studding the outer leaflet with charged nm-sized particles. Image analysis of time trajectories, obtained using epifluorescence imaging, was performed at sub-pixel resolution. This talk will emphasize aspects of curiously heterogeneous dynamics and also quantification of ``cage'' size in this system. Taken together, this system of charged, polydisperse, flexible objects displays rich dynamics that contrasts acutely with known behavior for hard-sphere dense particle systems.