Bulletin of the American Physical Society
76th Annual Gaseous Electronics Conference
Volume 68, Number 9
Monday–Friday, October 9–13, 2023; Michigan League, Ann Arbor, Michigan
Session IT4: Poster Session I; Exhibition & Coffee (4:00pm-6:00pm)
4:00 PM,
Tuesday, October 10, 2023
Room: Michigan League, Ballroom
Abstract: IT4.00064 : Cold atmospheric plasma for neural regeneration*
Presenter:
Gal Haspel
(Princeton Plasma Physics Laboratory)
Authors:
Gal Haspel
(Princeton Plasma Physics Laboratory)
Marcella Viola
(New Jersey Institute of Technology)
Maria Belen Harreguy
(New Jersey Institute of Technology)
Sophia Gershman
(Princeton Plasma Physics Laboratory)
We use the nematode C. elegans, a model system in many fields of biology; it is transparent with a fully mapped genome and neuronal connectome. Because C. elegans axon guidance involves conserved pathways as in vertebrates, it is an ideal model to study factors affecting axon regeneration. Our system allows us to address questions about the mechanism of action of plasma at molecular, cellular, and neural network levels, with available mutant strains and the transgenic manipulations we can perform. Further, we use genetically encoded fluorescent biosensors to measure changes in redox state and reactive oxygen species in live animals.
*The study is supported by DoE award DE‐SC0023430. Plasma source design and diagnostics were conducted at the Princeton Collaborative Research Facility (PCRF) supported by DOE through contract DE-AC02-09CH11466.
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