Bulletin of the American Physical Society
75th Annual Gaseous Electronics Conference
Volume 67, Number 9
Monday–Friday, October 3–7, 2022;
Sendai International Center, Sendai, Japan
The session times in this program are intended for Japan Standard Time zone in Tokyo, Japan (GMT+9)
Session EF1: Plasma Medical & Agricultural Application I |
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Chair: Kazunori Koga, Kyushu University Room: Sendai International Center Hagi |
Friday, October 7, 2022 8:00AM - 8:30AM |
EF1.00001: Air discharge plasma used for preventing SARS-CoV-2 infections Invited Speaker: Dingxin Liu The global pandemic caused by SARS-CoV-2 has lasted for more than two years and will still continue, so it is important to develop a new disinfection technology to stop the spread of the virus. Cold atmospheric plasma is well known to have a strong bactericidal effect, and here it is used for the inactivation of pseudoviruses with the SARS-CoV-2 S protein. According to the literature, SARS-CoV-2 infection depends on the recognition of and binding to the cellular receptor human angiotensin-converting enzyme 2 (hACE2) through the receptor-binding domain (RBD) of the S protein, and disruption of this process can effectively inhibit SARS-CoV-2 invasion. The plasma is generated by a surface dielectric barrier discharge in air, and two application scenarios are studied: One is for cold chain logistics which is considered as a main route of remote infection, and in that case (-20 ℃) the effluent gas of plasma is used for disinfection. It is found that either dried or the wet pseudovirus are effectively deactivated after exposure to plasma-treated air for 20 min, regardless of whether it is attached to flakes of plastic or a copper sheet. The deactivation effect is much stronger than that treated by the conventional ozone technology. The other is for contact transmission which is frequently happened, and in that case the plasma-activated water (PAW) is used for surface disinfection. It is found that the PAW could effectively inhibited pseudovirus infection through S protein inactivation. The RBD binding activity was inactivated by PAW through the RBD modification. The short-lived reactive species in the PAW, such as ONOO- , played crucial roles in this inactivation. Our findings provide evidence of a potent disinfection strategy to combat the epidemic caused by SARS-CoV-2. |
Friday, October 7, 2022 8:30AM - 8:45AM |
EF1.00002: Investigation of Plasma-generated Reactive Species Responsible for Human Coronavirus Inactivation Shota Sasaki, Shion Osana, Mutsuo Yamaya, Hidekazu Nishimura, Ryoichi Nagatomi, Toshiro Kaneko The recent global pandemic of Corona Virus Disease-19 (COVID-19) has impacted all aspects of society, producing a growing demand for a powerful virus inactivation method. To assess a potential and mechanism of human coronavirus inactivation using atmospheric pressure plasma (APP) technology, infectivities of human coronavirus 229E (HCoV-229E) after various APP treatments were evaluated. Exposure of HCoV-229E solution to a helium (He) APP for 30 s significantly reduced the HCoV-229E virus titers (3 log10TCID50 reduction). This shows a powerful virus-inactivation efficacy of the APP. The experiments with the H2O2/NO2−supplement and the 5 types of RONS scavengers indicated that O2•− and/or O2•−-derived species can be important for the APP-induced virus inactivation while other short-lived RONS (•OH, 1O2, •NO) and long-lived RONS (H2O2, NO2−, NO3−) could not contribute, specifically even though very high-rate of •OH production (~1.7 nmol/s). In the presentation, separate contribution of reactive species generated by various APP devices will be discussed. |
Friday, October 7, 2022 8:45AM - 9:00AM |
EF1.00003: Optimized treatment approach for inactivation of Escherichia coli and Klebsiella pneumoniae through non-thermal plasma Milad Rasouli, Elham Hamidi, Bizhan Farokhi, Majid Mahdieh, Mahmood Ghoranneviss Non-thermal plasma is a high-energy gas created when an electric current is passed through a gas. The use of plasma on sensitive materials such as human tissue, food products, medical services, and the packaging industry was therefore impractical. However, over the last year, technological breakthroughs have made it possible to produce low-temperature plasma under atmospheric conditions, providing many advantages. Plasmas have shown success in the decontamination of a wide range of microorganisms, including bacteria and fungi, and have even shown success in damaging bacteria spores. Traditional methods of sterilization have disadvantages such as the thermal effect and the production of toxic and chemical residues. In our research, we have presented an applicable and outstanding device for sterilization. The dielectric barrier discharge (DBD) is a low temperature and atmospheric pressure plasma source that is created between two conductive electrodes connected to an AC power supply. At least one of the electrodes is covered by the dielectric layer. To study the effect of DBD plasma on bacteria, we studied its inactivation influence on Escherichia coli and Klebsiella. The result of DBD plasma treatment of Escherichia coli and Klebsiella shows that complete sterilization occurs after 30 s, 60 s, and 90 s of exposure time without any thermal effect, and increasing the exposure time and voltage increases the inactivation effect of cold plasma. So, non-thermal and non-destructive methods could be used to kill bacteria and other agents that cause infections in hospitals. |
Friday, October 7, 2022 9:00AM - 9:15AM |
EF1.00004: Characterization of Novel Flexible Surface Dielectric Barrier Discharge Electrodes for the Purpose of In-Package Microbe Deactivation on the Surface of Fresh Produce Duncan P Trosan, Patrick D Walther, Qingyang Wang, Stephen D Mclaughlin, Aaron Mazzeo, Deepti Salvi, Katharina Stapelmann
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Friday, October 7, 2022 9:15AM - 9:30AM |
EF1.00005: An Efficient Two-stage Type Electrostatic Precipitator for Aerosol Collection Operated by Compact Pulsed Power Generator Katsuyuki Takahashi, Ryo Saito, Takuto Kikuchi, Riku Yamaguchi, Koichi Takaki, Akinori Zukeran, Tatsuya Terazawa, Yasuyuki Ito A two-stage type electrostatic precipitator operated by a pulsed power generator is developed for highly efficient aerosol collection. A compact and light weight inductive pulsed power generator driven by SiC-MOSFET with a diode rectifier is developed to generate a nano-second pulsed voltage superimposed on a DC bias voltage. The amplitude and pulse width of the pulsed voltage are 7.5 kV and 130 ns, respectively, and the maximum DC bias voltage is 4 kV. The pulsed voltage is applied to a plurality of wire-wire electrode to generate streamer discharges, and a DC voltage of -2 kV is applied to a plurality of plate-plate electrode used as collecting electrodes. A nebulizer is used to produce aerosol droplets which have diameters of sub-micrometers. The aerosol collection efficiency increases with increasing the DC bias voltage and reaches 100% with the DC bias voltage higher than 2.5 kV. |
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