Bulletin of the American Physical Society
68th Annual Gaseous Electronics Conference/9th International Conference on Reactive Plasmas/33rd Symposium on Plasma Processing
Volume 60, Number 9
Monday–Friday, October 12–16, 2015; Honolulu, Hawaii
Session UF1: Plasma Sources for Biomedical Applications II |
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Chair: Stephan Reuter, INP, Greifswald Room: 301 B |
Friday, October 16, 2015 1:30PM - 2:00PM |
UF1.00001: Atmospheric non-equilibrium plasma sources and processes with a focus on plasma medicine {\&} antibacterial applications Invited Speaker: Vittorio Colombo Non-equilibrium atmospheric pressure plasmas (NTPs) offer an astounding versatility, relying on a wide range of physical principles and source architectures for their generation and sustainment; spanning from DBDs to plasma guns, from jet-to-jet coupled sources to hot plasmas at the production site. NTPs are being explored for an ever increasing number of biomedical and therapeutic applications. The talk will mainly consider the following subjects: investigation of the antimicrobial activity of a low power ICP source at safe levels for eukaryotic cells; investigation of antibacterial efficacy of a plasma gun source for endodontic applications; antimicrobial activity induced in static water by a DBD reactor driven by nanosecond pulses. Some preliminary results will also be given for in vivo investigation on the effects of plasma activated water against plant pathogenic bacteria and for the study on the effectiveness of a jet-to-jet coupled nanopulsed source for localized bacterial inactivation.\\[4pt] In collaboration with Daniela Barbieri, Marco Boselli, Matteo Gherardi, Romolo Laurita, Anna Liguori, Emanuele Simoncelli, Augusto Stancampiano, and Enrico Traldi, Alma Mater Studiorum - Universit\`a di Bologna, Department of Industrial Engineering - Italy. [Preview Abstract] |
Friday, October 16, 2015 2:00PM - 2:15PM |
UF1.00002: Development of an innovative low temperature DBD plasma source based on a flexible textile layer for medical applications J.-S. Baudler, S. Horn, A. Quade, K.-D. Weltmann Plasma sources for medical applications are usually expensive and inconvenient due to big dimensions or the need for special infrastructure. Our approach is to design a plasma source which will not only solve these problems, so it can also be mass produced at comparatively small costs. this presentation we will show a short overview about the whole development process of such a device. We will start with the idea, including CAD, electric field simulation and proof of concept. Afterwards we will proceed to the prototype design and manufacturing including material choice, electrical control and conducting the first antimicrobial tests. The most important role during the development was the choice of materials for the dielectric barrier. The barrier is responsible for several important factors like required voltage, system capacity and user security. We will show that the class of fluoropolymers is one of the best choices here, but with the risk of harmful degradation products. Due to medical restrictions we had to look after these products with the widely used PTFE in mind. To estimate this risk we have used VUV-Spectroscopy to look in-vivo after the creation of the ArF excimer as a relative indicator for the degradation processes. When we observed this indicator we searched for ways to lower the risk. We ended up with two possible solutions: the defluorisation of the surface and lowering the overall system energy by electrode design. We compared both with our initial results to estimate the effectiveness of the methods. [Preview Abstract] |
Friday, October 16, 2015 2:15PM - 2:30PM |
UF1.00003: Interaction of AC excited Atmospheric Pressure Ar Plasma Jet with Medium Keigo Takeda, Sijie Liang, Takumi Kumakura, Kenji Ishikawa, Hiromasa Tanaka, Makoto Sekine, Masaru Hori Recently, there are interesting results on the plasma selective killing of cancer cells against normal cells using the atmospheric pressure plasma. In the applications, the interaction of plasma with liquid is a hot research topic since most cells and tissues are surrounded by liquids. In the cases, reactive species in gas phase play important roles on the generation of reactive species in the medium. Therefore, it is strongly required to diagnose the behaviors of gas-phase reactive species for clarification of the interactive reactions of plasma jet with the medium. In this study, the interaction of an AC excited argon atmospheric pressure plasma jet (APPJ) with medium have been investigated on the basis of behaviors of gas-phase OH radical measured by using optical emission spectroscopy and laser induced spectroscopy. From the results, the OH radical was observed only in the plasma jet for irradiating the medium with the plasma jet. Therefore, in the AC excited APPJ treatment, it is considered that OH radical is mainly generated by dissociation of water vapor in ambient air and the effects of OH radical on generation of reactive species in the medium decreased with increase in the distance between plasma head and medium surface. [Preview Abstract] |
Friday, October 16, 2015 2:30PM - 3:00PM |
UF1.00004: Long-Term Preservation of Marine Products via Conformational Change of Protein by Electrostatic Effect Invited Speaker: Koichi Takaki Conformational change of Bovine Serum Albumin (BSA) by AC electric field was studied experimentally for long-term preservation of marine products. The AC voltage was generated with a transformer that had an amplitude of 10 kV and a frequency of 50 Hz. High AC voltage was applied to a metal shelf located in an incubator. The experimental results suggested that the conformation of protein changed from $\alpha $-helix to $\beta $-sheet by applying AC voltage during the preservation. The denaturation of the protein with the temperature change was suppressed by the AC voltage treatment. The AC electric field was also applied during freezing to improve the freshness. Both sample groups were cryopreserved and placed in each incubator at $-$10 $^{\circ}$C for 20 days. The freshness was estimated by the amount of the proteins with the molecular weight of less than 70,000 included in the drip which eluted from samples called SDS polyacrylamide gel electrophoresis. It was found that the amount of the protein with the molecular weight of less than 70,000 decreased by applying the AC high voltage. The degeneration in proteins was inhibited by the effect of the AC high voltage. This experimental results showed that the use of AC voltage during freezing is effective for preserving the freshness of the perishable foods.\\[4pt] In collaboration with Takanori Ito, Takamasa Okumura, Katsuyuki Takahashi, Sumio Aisawa, Shigeyoshi Yamazaki, and Bunei Syuto, Iwate University. [Preview Abstract] |
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