Bulletin of the American Physical Society
64th Annual Meeting of the APS Division of Plasma Physics
Volume 67, Number 15
Monday–Friday, October 17–21, 2022; Spokane, Washington
Session GP11: Poster Session III: In-Person, Hall A (9:30-11:00am) and Virtual Poster Presentations (11:15am-12:30pm)
MFE: DIII-D
Low Temperature Plasma
FUND: Dusty Plasmas; Plasma Sources
9:30 AM - 12:30 PM
Tuesday, October 18, 2022
Room: Exhibit Hall A and Online
Abstract: GP11.00077 : Cold atmospheric plasma for neural regeneration*
Presenter:
Gal Haspel
(Department of Biological Sciences, New Jersey Institute of Technology)
Authors:
Gal Haspel
(Department of Biological Sciences, New Jersey Institute of Technology)
Maria Belen Harreguy
(Department of Biological Sciences, New Jersey Institute of Technology)
Sophia Gershman
(Plasma Science and Technology Group, Princeton Plasma Physics Laboratory)
We use the nematode C. elegans that is a model system in many fields of biology; it is transparent with fully mapped genome and neuronal connectome. Because C. elegans axon guidance involves conserved pathways as in vertebrates, it is an ideal model to study factors affecting axon regeneration. Our system allows us to address questions about the mechanism of action of plasma at molecular, cellular, and neural network levels, with available mutant strains and the transgenic manipulations we can perform. Further, we use genetically encoded fluorescent biosensors to measure changes of redox state and reactive oxygen species in live animals.
*The work of SG was supported by the Princeton Collaborative Research Facility (PCRF), which is supported by the U.S. Department of Energy (DOE) under Contract No. DE-AC02-09CH11466. Resources used for plasma source design, construction, and diagnostics were provided by the PCRF.
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