Bulletin of the American Physical Society
76th Annual Meeting of the Division of Fluid Dynamics
Sunday–Tuesday, November 19–21, 2023; Washington, DC
Session X08: Biofluids: Lymphatic and CSF Flows II
8:00 AM–10:36 AM,
Tuesday, November 21, 2023
Room: 103B
Chair: Francisca Guzmán-Lastra, Universidad de Chile
Abstract: X08.00009 : Influence of respiration frequency and depth on the flow of CSF in the spinal canal*
9:44 AM–9:57 AM
Presenter:
Mariano Rubio-Rubio
(Univ. Carlos III de Madrid)
Authors:
Mariano Rubio-Rubio
(Univ. Carlos III de Madrid)
Wilfried Coenen
(Univ. Carlos III de Madrid)
José Ignacio Jiménez-González
(Univ. de Jaén)
Candido Gutierrez-Montes
(Univ. de Jaén)
Marta Vidorreta
(Siemens Healthineers)
Guillermo Rus
(Univ. de Granada)
Antonio L Sanchez
(University of California, San Diego)
Victor Haughton
(University of Wisconsin-Madison)
Carlos Martínez-Bazán
(Univ. de Granada)
In this work, we present measurements of CSF flow during normal, controlled, respiration using real-time MR imaging at the cervical and lumbar level, synchronized with measurements of respiratory flow rate. We examine the influence of different respiration frequencies and depths on the induced CSF velocities. Our results reveal the existence of a clear effect of respiratory period and intensity on the induced CSF flow and associated stroke volume, especially in the lumbar region, where it is found to be the dominant driving mechanism.
*Supported by National Institute of Health through grant R01NS120343-01, Spanish MINECO through grant PID2020-115961 and Junta Andalucía and European Funds through grant P18-FR-4619.
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