Bulletin of the American Physical Society
76th Annual Meeting of the Division of Fluid Dynamics
Sunday–Tuesday, November 19–21, 2023; Washington, DC
Session S01: Poster Session & Refreshment Break IV (3:34 - 4:25 p.m.)
3:34 PM,
Monday, November 20, 2023
Room: Exhibit Hall D
Abstract: S01.00059 : Transporting macrophages with magnetic helical microrobots
Presenter:
Ritu R Raj
(University of Colorado, Boulder)
Authors:
Ritu R Raj
(University of Colorado, Boulder)
Nicole B Day
(University of Colorado, Boulder)
Elizabeth Cutting
(University of Colorado, Boulder)
Nichole Loomis
(University of Colorado, Boulder)
Ankur Gupta
(University of Colorado, Boulder)
Wyatt Shields
(University of Colorado, Boulder)
Helical microrobots, 50 microns in size, were fabricated with two-photon lithography and coated with chromium, nickel, and titanium to endow magnetic responsiveness in a biocompatible shell. Macrophages were added to the helices and cell attachment was characterized. The locomotion of the cell/microrobot complexes were studied in the presence of a rotating magnetic field.
We found that the location of cell attachment had a deterministic effect on the motion of the microrobot. Cells attached to the ends of the helices had a minor effect on the magnitude and direction of the microrobot velocity compared to cells inside and along the sides of the helices. We explain the alteration to locomotive modes via simulations of microrobot translation and rotation to determine changes in hydrodynamic mobility. This understanding can be leveraged to improve the efficacy of microrobots in biomedical and environmental remediation applications.
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