Bulletin of the American Physical Society
76th Annual Meeting of the Division of Fluid Dynamics
Sunday–Tuesday, November 19–21, 2023; Washington, DC
Session J14: Biofluids: Small Vessels and Microcirculation I
4:35 PM–6:19 PM,
Sunday, November 19, 2023
Room: 144AB
Chair: Peter Balogh, New Jersey Institute of Technology
Abstract: J14.00005 : Organization and dynamics of red blood cells in a stenosed microchannel under time-dependent flow*
5:27 PM–5:40 PM
Presenter:
Steffen M Recktenwald
(Saarland University)
Authors:
Steffen M Recktenwald
(Saarland University)
Katharina Graessel
(University of Bayreuth)
Yazdan Rashidi
(Saarland University)
Thomas John
(Saarland University)
Stephan Gekle
(University of Bayreuth)
Christian Wagner
(Univ des Saarlandes)
This study investigates RBC organization and CFL dynamics under time-dependent flow. We use a high-precision pressure device to pump RBC suspensions with concentrations ranging from 1% to 20% in volume through a microfluidic constriction. We employ a sinusoidal pressure modulation to examine the time-dependent CFL and perform high-speed optical microscopy at various positions before and after the constriction. The resulting image sequences are synchronized with the phase of the driving and post-processed with a customized routine that allows us to determine the RBC core flow even at low concentrations and under time-dependent flow conditions. Our results highlight the dominant effects of the RBC concentration and the amplitude of the applied pressure signal on the CFL dynamics. Complementary numerical simulations reveal how the time-dependent CFL is coupled with the dynamically changing flow field at the constriction. Our study provides crucial insight into the flow behavior of complex fluids in unsteady microscale flows.
*This work was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Project No. 349558021 (RE 5025/1-2, WA 1336/13-1, and GE 2214/2-1). K.G. thanks the Studienstiftung des Deutschen Volkes for financial support.
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