Bulletin of the American Physical Society
71st Annual Meeting of the APS Division of Fluid Dynamics
Volume 63, Number 13
Sunday–Tuesday, November 18–20, 2018; Atlanta, Georgia
Session KP1: Poster Session (3:20-4:05pm)
Monday, November 19, 2018
Georgia World Congress Center Room: Level 1, Exhibit Hall B2 by the GFM videos
Abstract ID: BAPS.2018.DFD.KP1.25
Abstract: KP1.00025 : Development of a functional ex-vivo porcine heart system to test and improve heart valve repairing techniques*
(Author Not Attending)
Fully functional heart valves are integral to a healthy heart. Defective valves cause regurgitation, decreased cardiac output, and heart failure. Developing improved methods of heart valve repair typically involves performing the procedure on a pig in vivo, as pigs’ hearts are anatomically and physiologically very similar to humans’. However, a porcine ex vivo heart model can provide a reliable intermediate step before in vivo procedures to save resources on initial testing. In this study, the ex vivo left heart model is designed, developed, and analyzed to test its ability to emulate an in vivo beating heart for surgical testing. A pulsatile pump was connected to an explanted porcine heart to mimic the physiological beating of the heart, and saline solution was pumped through the heart to mimic blood flow. Damage was induced on the heart valves. Hemodynamic parameters such as cardiac output and ventricular pressure were measured with flow and pressure sensors before damage, after damage, and after surgical repair to assess the model’s accuracy and the repair’s effectiveness.
*I would like to thank the Samuel Ginn College of Engineering and the Office of Undergraduate Research at Auburn University for jointly providing ancillary funds for this research.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.DFD.KP1.25
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