Bulletin of the American Physical Society
2018 Annual Meeting of the APS Four Corners Section
Volume 63, Number 16
Friday–Saturday, October 12–13, 2018; University of Utah, Salt Lake City, Utah
Session G01: Poster Session
5:00 PM,
Friday, October 12, 2018
CSC
Room: 205/206
Chair: David Kieda, University of Utah
Abstract ID: BAPS.2018.4CS.G01.27
Abstract: G01.00027 : Microtubule stability and mechanical rigidity at high temperatures*
Presenter:
Abhimanyu Sharma
(Univ of Utah)
Author:
Abhimanyu Sharma
(Univ of Utah)
Microtubules (MT) are polymers of α and β tubulin and constitute a significant part of eukaryotic cell’s cytoskeleton. They are tubules, ~25nm in diameter and can extend up to several tens of microns in length. They can be crudely modeled mechanically as rigid rods but many finer details linked to their structural anisotropy remain controversial. Understanding these finer mechanical properties is important biologically as well as for bio-nano engineering applications.
The effect of temperature variation on mechanical properties of MT is yet to be fully understood. We will discuss the flexural rigidity of taxol-stabilized MTs as a function of temperature and the implications of our results for how MT structure impacts their temperature stability. We’ve also tested the limits of MT stability at high temperatures and different factors that contribute to it.
*National Science Foundation (NSF) University of Utah Research foundation
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.4CS.G01.27
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