Bulletin of the American Physical Society
APS March Meeting 2019
Volume 64, Number 2
Monday–Friday, March 4–8, 2019; Boston, Massachusetts
Session X59: Soft Composites: Mechanics and Structure I
8:00 AM–10:48 AM,
Friday, March 8, 2019
BCEC Room: 257B
Sponsoring Unit: GSOFT
Chair: Rae Robertson-Anderson, University of San Diego
Abstract: X59.00001 : Glassy Dynamics in Composite Biopolymer Networks*
8:00 AM–8:36 AM
Josef A. Kas
(German Cancer Research Center)
David M Smith
(Fraunhofer Institute for Cell Therapy and Immunology)
Here, these effects caused by composite structures will be especially addressed with the two key elements of the cytoskeleton actin and vimentin IF. In contrast to previous studies, entangled conformations of these reconstituted composite networks can be described by a superposition of two non-interacting scaffolds. Key elements are the ability to compare different compositions with comparable architectural features as well as to identify polymer-specific interactions, which are typically ignored in most established models. We have experimentally identified inter-filament interactions as a key factor that can overwrite scaling predictions of the classical semiflexible polymer physics by comparing results of networks of actin, vimentin IF, keratin IF and synthetic double-crossover DNA nanotubes.
Acquired results of the linear and non-linear bulk mechanics are captured in the frame of an inelastic glassy wormlike chain model allowing to address the diversity of the polymer types based on their specific interactions, which lead to differing relaxation behaviors for the different polymer types. Accounting for this molecular diversity, the composite effects can be expressed as a superposition of the non-interacting scaffolds.
We acknowledge funding by the Deutsche Forschungsgemeinschaft (DFG) and by
the European Research Council (ERC).
The American Physical Society (APS) is a non-profit membership organization working to advance the knowledge of physics.
1 Physics Ellipse, College Park, MD 20740-3844
Editorial Office 1 Research Road, Ridge, NY 11961-2701 (631) 591-4000
Office of Public Affairs 529 14th St NW, Suite 1050, Washington, D.C. 20045-2001 (202) 662-8700