Bulletin of the American Physical Society
APS March Meeting 2019
Volume 64, Number 2
Monday–Friday, March 4–8, 2019; Boston, Massachusetts
Session E34: Radiation Detection and Monitoring in Medical Imaging and TherapyInvited
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Sponsoring Units: GMED Chair: Wojciech Zbijewski, Johns Hopkins University Room: BCEC 205A |
Tuesday, March 5, 2019 8:00AM - 8:36AM |
E34.00001: Modeling of Detector Performance Invited Speaker: Jeffrey Siewerdsen Recent advances in medical imaging include the development of large-area flat-panel x-ray detectors for radiography, fluoroscopy, mammography, and cone-beam CT as well as multi-detector and photon counting systems for diagnostic CT. Such advances have enabled new capabilities (for example, improved spatial resolution and reduced radiation dose) and propelled a revolution in 3D imaging systems over the last two decades. Quantitative understanding of the performance of various detector technologies - and optimizing their performance for a particular clinical application - benefits tremendously from mathematical models of imaging performance, including analytical models of spatial resolution, noise, and detective quantum efficiency. Such models give insight on the performance of each element of the imaging chain in terms of its spatial-frequency-dependent transfer characteristics. In turn, these characteristics can be related to the performance of a particular imaging task by considering spatial-frquency-dependent signal and noise with respect to the spatial-frequencies associated with performance of a particular task - i.e., "task-based" models. Such analysis has provided a foundation for imaging chain optimization (including scintillator thickness, pixel pitch, and electronic readout noise) and helped to accelerate the development of new imaging systems for 2D (projection) and 3D (volumetric) imaging systems for a variety of applications in medical diagnosis and interventional guidance. In this presenationa, we review the essentials of such task-based models of imaging performance, study examples of model-based design of new imaging systems, and consider future challenges in modeling of nonlinear imaging systems. |
Tuesday, March 5, 2019 8:36AM - 9:12AM |
E34.00002: New Scintillators for Medical Imaging Invited Speaker: Vivek Nagarkar Microcolumnar growth technology represents a major advance for novel inorganic/oxide scintillators designed for high-efficiency high-resolution detection and imaging by means of X-rays or neutrons. Unlike powdered screens, the microcolumnar structure acts to channel the scintillator light directly towards the detector with minimal lateral spread, which greatly reduces need for tradeoff between efficiency and spatial resolution. RMD has played a major role in this development, and with our expertise in materials and our basic understanding of production of structured CsI:Tl films, we have successfully tailored performance of scintillators for various specific applications. Adapted methodologies include: |
Tuesday, March 5, 2019 9:12AM - 9:48AM |
E34.00003: Detector Technology for Photon Counting CT Invited Speaker: Mats Danielsson Photon Counting detectors is a logic next step for CT. This technique will enable higher contrast and/or lower radiation dose. In particular lower concentrations of Iodine can be detected and quantified which is important in angiography or perfusion imaging. Moreover beam hardening artefacts will disappear with material base decomposition. Electronic noise can be completely eliminated by using a minimum threshold which will help imaging of large patients and enable reduced radiation dose compared to what is possible today. We will outline the state-of-the-art for photon counting imaging detector technology and how the major challenges such as high rates (pile-up), charge sharing (energy resolution) and absorption efficiency can be addressed and what the tradeoffs are. The direct conversion detectors used for photon counting will enable smaller pixels than what is feasible with today's scintillators and we expect the higher spatial resolution in combination with the increased spectral performance to be a powerful combination for example in imaging of the coronary arteries. |
(Author Not Attending)
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E34.00004: Range Verification of Proton Therapy Beams Invited Speaker: Joost Verburg TBD |
Tuesday, March 5, 2019 10:24AM - 11:00AM |
E34.00005: Targeted Radionuclide Therapy Invited Speaker: Robert Jeraj TBD |
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