Bulletin of the American Physical Society
APS March Meeting 2018
Monday–Friday, March 5–9, 2018; Los Angeles, California
Session V06: Physics of Neural Networks
2:30 PM–5:18 PM,
Thursday, March 8, 2018
LACC Room: 153A
Sponsoring Units: DBIO GSNP
Chair: William Bialek, Princeton Univ
Abstract: V06.00004 : Temporal Organization of Neuronal Avalanches at Criticality
3:06 PM–3:18 PM
Lucilla De Arcangelis
(University of Campania)
Bursty dynamics characterizes many physical systems. In neuronal networks the near synchronous firing of many neurons gives rise to the so-called neuronal avalanches, a collective phenomenon that is a key feature of the resting brain activity. Experiments at all spatial scales have evidenced that neuronal avalanche sizes and durations follow power law distributions, a typical feature of systems at criticality. Yet, avalanche dynamics in neuronal systems remain poorly understood. In this talk I will focus on the relationship between criticality and temporal structure of avalanches in cortex slice cultures.
I will first show that waiting time distributions for avalanches follow a common non-monotonic behavior, featuring a power law at short (< 1s) timescales followed by a local minimum and an exponential tail(Phys.Rev.Lett.108,2012). Using numerical simulations, I'll demonstrate that this peculiar behavior arises from the alternation of two different network states, the up and down-state, and that the specific temporal organization of neuronal avalanches is closely related to the criticality of the system. Finally, I'll discuss the dynamical relationship between avalanches and waiting times, and its connection with excitatory and inhibitory network features(Chaos,27,2017).
The American Physical Society (APS) is a non-profit membership organization working to advance the knowledge of physics.
1 Physics Ellipse, College Park, MD 20740-3844
Editorial Office 1 Research Road, Ridge, NY 11961-2701 (631) 591-4000
Office of Public Affairs 529 14th St NW, Suite 1050, Washington, D.C. 20045-2001 (202) 662-8700