Bulletin of the American Physical Society
APS March Meeting 2018
Volume 63, Number 1
Monday–Friday, March 5–9, 2018; Los Angeles, California
Session P48: Motion and Jamming of Cells
2:30 PM–5:18 PM,
Wednesday, March 7, 2018
LACC
Room: 510
Sponsoring
Units:
GSNP GSOFT DBIO
Chair: Mark Shattuck, City College of New York CUNY
Abstract ID: BAPS.2018.MAR.P48.5
Abstract: P48.00005 : Relaxation of self-induced jamming in confined budding yeast population
3:42 PM–3:54 PM
Presenter:
Marie-Cécilia Duvernoy
(University of California, Berkeley)
Authors:
Marie-Cécilia Duvernoy
(University of California, Berkeley)
Pawel Gniewek
(University of California, Berkeley)
Carl Schreck
(University of California, Berkeley)
Oskar Hallatschek
(University of California, Berkeley)
When grown in deformable micro-chambers that mimic these conditions, budding yeast cells displays features of jammed systems, as they build up large mechanical pressures resulting of heterogeneous forces inside the cell population. Such high pressure are sufficient to impact the population’s growth rate and eventually stall the cells, as individuals do not commit to division anymore (blocked in G1). We will present evidence that this phenotype is reversible if confinement is suddenly released and look at the relaxation process in terms of physical and physiological observables.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.MAR.P48.5
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