Bulletin of the American Physical Society
APS March Meeting 2018
Monday–Friday, March 5–9, 2018; Los Angeles, California
Session B13: Complex Oxide Heterostructures - Synthesis Techniques and Strain Effects
11:15 AM–1:27 PM,
Monday, March 5, 2018
LACC Room: 304A
Sponsoring Unit: DMP
Chair: Divine Kumah, North Carolina State University
Abstract: B13.00011 : Interaction of Stem Cells with Metal Oxide Thin Films*
1:15 PM–1:27 PM
(Laboratoire CRISMAT, CNRS/ENSICAEN/UNICAEN)
Stem cells are extensively studied due to their unique properties and great potential in biomedical applications. Thanks to a variety of biological responses, metal-oxide coatings are widely used for interacting with stem cells. A very limited number of oxides have however been studied, and mechanism of the cell-material interaction is still not completely clear.
Here, oxides thin films, that are well-known for their electronic properties, are deposited on substrates using the pulsed laser deposition (PLD) technique. Bone marrow mesenchymal stem cells were cultured on the surfaces of thin films and their adhesion, proliferation and differentiation were evaluated as a function of the growth conditions, thickness of the films, surface roughness and morphology. These results will be of a great clinical significance, in particular, in the field of regenerative medicine.
*Support from Normandie Université for her PhD fellowship. Partial support from project Emergence Normandie, and the FEDER are also acknowledged.
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