Bulletin of the American Physical Society
APS March Meeting 2015
Volume 60, Number 1
Monday–Friday, March 2–6, 2015; San Antonio, Texas
Session M19: Invited Session: Industry Day: Progress and Challenges of Additive Manufacturing |
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Sponsoring Units: FIAP DPOLY Chair: Miriam Rafailovich, State University of New York, Stonybrook Room: Mission Room 103B |
Wednesday, March 4, 2015 11:15AM - 11:51AM |
M19.00001: Advances in Additive Manufacturing Invited Speaker: Vlastimil Kunc |
Wednesday, March 4, 2015 11:51AM - 12:27PM |
M19.00002: 3D Printing of Human Tissue Mimics via Layer-by-Layer Assembly of Polymer/Hydrogel Biopapers Invited Speaker: Bradley Ringeisen The foundations of tissue engineering were built on two fundamental areas of research: cells and scaffolds. Multipotent cells and their derivatives are traditionally randomly seeded into sophisticated polymer or hydrogel scaffolds, ultimately with the goal of forming a tissue-like material through cell differentiation and cell-material interactions. One problem with this approach is that no matter how complex or biomimetic the scaffold is, the cells are still homogeneously distributed throughout this three dimensional (3D) material. Natural tissue is inherently heterogeneous on both a microscopic and macroscopic level. It also contains different types of cells in close proximity, extracellular matrix, voids, and a complex vascularized network. Recently developed 3D cell and organ printers may be able to enhance traditional tissue engineering experiments by building scaffolds layer-by-layer that are crafted to mimic the microscopic and macroscopic structure of natural tissue or organs. Over the past decade, my laboratory has developed a capillary-free, live cell printer termed biological laser printing, or BioLP. We find that printed cells do not express heat shock protein and retain \textgreater 99{\%} viability. Printed cells also incur no DNA strand fracture and preserve their ability to differentiate. Recent work has used a layer-by-layer approach, stacking sheets of hybrid polymer/hydrogel biopapers in conjunction with live cell printing to create 3D tissue structures. Our specific work is now focused on the blood-brain-barrier and air-lung interface and will be described during the presentation. [Preview Abstract] |
Wednesday, March 4, 2015 12:27PM - 1:03PM |
M19.00003: 3-D Constructs--Molded vs. Printed: The differences from a cell based perspective Invited Speaker: Marcia Simon Additive manufacturing technologies are increasingly being used to replace standard extrusion or molding methods in engineering polymeric biomedical implants and devices. The principal advantage of this new technology is the ability to print directly from a scan and hence produce parts which are an ideal fit for an individual, which eliminates much of the sizing and fitting associated with standard manufacturing methods. The question though arises whether devices which may be macroscopically similar, serve identical functions, and be produced from the same polymeric material, in fact interact in the same manner with living tissue. Here we will discuss the differences in the surface structures produced by these manufacturing methods and the interactions of dental pulp stem cells with structures of multiple length scales as they impact cell differentiation and tissue mineralization.\\[4pt] In collaboration with Kuan Che Feng, Mariah Geritano, Michael Cuiffo, and Gary Halada, Materials Science and Engineering, Stony Brook University; Adriana Pinkas-Sarafova, Oral Biology and Pathology and Materials Science and Engineering, Stony Brook University; Sihana Rugova, Oral Biology and Pathology, Stony Brook University; and Miriam Rafailovich, Materials Science and Engineering, Stony Brook University. [Preview Abstract] |
Wednesday, March 4, 2015 1:03PM - 1:39PM |
M19.00004: Novel Patterning Approaches for Continued Device Scaling Invited Speaker: Florian Gstrein Top-down patterning techniques based on optical lithography have made semiconductor products ever more powerful, ubiquitous and affordable. This is largely due to the ability of conventional lithographic techniques to transfer trillions of mask features to wafers at defect densities approaching virtually zero in high-volume manufacturing. As features continue to shrink, the ability to print and to correctly place tight-pitch patterns have quickly emerged as two of the greatest challenges to scaling. Given the fundamental physical limitations of conventional optical lithography, complimentary patterning techniques and bottom-up patterning approaches are needed to overcome shortcomings in resolution and pattern placement accuracy. This presentation will focus on the enabling role novel materials can play in achieving both critical dimension scaling and reduced pattern placement errors. The talk will first outline how extreme UV lithography (EUV) and directed self-assembly (DSA) can simplify patterning and improve multilayer pattern placement by reducing the number of masks and associated overlay steps required to achieve the desired resolution. Novel EUV resist materials require amplification mechanisms that overcome acid blur and new strategies to improve shot noise limitations and mechanical stability. For DSA, novel block co-polymers are needed with a higher chi parameter to yield tighter pitch and improved roughness. The second part of the talk will highlight opportunities for self-aligned patterning with a special emphasis on the emerging field of selective deposition. Atomic layer deposition (ALD) is derived from the chemical nature of precursors and co-reactants. The ability of these molecules to recognize chemical functionalities of surfaces, results in the deposition of thin films only where they are desired. Selective deposition is a powerful and so far unexploited patterning tool capable of further reducing or even eliminating pattern placement errors. [Preview Abstract] |
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