Session Y45: Focus Session: Physics of Cancer II

8:00 AM–11:00 AM, Friday, March 22, 2013
Hilton Baltimore Room: Holiday Ballroom 4

Sponsoring Unit: DBIO
Chair: Larry Nagahara, National Institutes of Health

Abstract ID: BAPS.2013.MAR.Y45.10

Abstract: Y45.00010 : Evolution of radiation resistance in a complex microenvironment

10:12 AM–10:24 AM

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Authors:

  So Hyun Kim
    (Ehwa Womans University)

  Robert Austin
    (Princeton University)

  Monal Mehta
    (Cancer Institute of New Jersey)

  Atif Kahn
    (Cancer Institute of New Jersey)

Radiation treatment responses in brain cancers are typically associated with short progression-free intervals in highly lethal malignancies such as glioblastomas. Even as patients routinely progress through second and third line salvage therapies, which are usually empirically selected, surprisingly little information exists on how cancer cells evolve resistance. We will present experimental results showing how in the presence of complex radiation gradients evolution of resistance to radiation occurs.

To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2013.MAR.Y45.10