Bulletin of the American Physical Society
APS March Meeting 2011
Volume 56, Number 1
Monday–Friday, March 21–25, 2011; Dallas, Texas
Abstract: S1.00129 : A temperature-dependent study of the low-frequency vibrational excitations in polynucleotides in solution
Author:
Far-infrared spectroscopy is a useful probe of low-frequency
collective
excitations of biomolecules, including DNA. These vibrational
modes are
believed to be related to conformational changes that occur in these
molecules during their biological function and, therefore, are very
important to study. In order to further our understanding of
these modes,
THz spectroscopy experiments were performed on solutions of
polynucleotides
between 20 to 100 cm$^{-1}$ from room temperature to 90
$^{\circ}$C, covering
the premelting and melting regimes. The samples studied include
Poly(dA-dT),
Poly(dA)-Poly(dT), Poly(dI-dC) and Poly(dI)-Poly(dC). Of particular
interest, the intensity of a band at about 67 cm$^{-1}$ is
observed to
increase as the melting proceeds.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2011.MAR.S1.129
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