Session V43: Focus Session: Translocation Through Nanopores II
8:00 AM–11:00 AM, Thursday, March 24, 2011
Room: A306/307
Sponsoring Units:
DPOLY DBP
Chair: Johan Dubbeldam, Delft University of Technology, Netherlands
Abstract ID: BAPS.2011.MAR.V43.1
Abstract: V43.00001 : The Statistics of DNA Capture and Re-Capture by Solid-State Nanopores
8:00 AM–8:12 AM
Preview Abstract
MathJax On | Off Abstract 
Authors:
Mirna Mihovilovic
(Brown University)
Erin Teich
(Brown University)
Nick Hagerty
(Brown University)
Jason Chan
(Brown University)
Derek Stein
(Brown University)
We studied repeated electrophoretic translocations of the same DNA molecule through $\sim $10 nm nanopores using the voltage-reversal re-capture technique. Correlations were observed in the folding conformations of molecules re-captured within the Zimm relaxation time of the polymer. A trend was observed, whereby more compact conformations of DNA evolved over time. Consecutive event charge deficit measurements were narrowly distributed about a well defined mean, suggesting that the analysis of multiple translocations through a pore can be used to improve estimates of the length of long polymers.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2011.MAR.V43.1