Bulletin of the American Physical Society
APS March Meeting 2011
Volume 56, Number 1
Monday–Friday, March 21–25, 2011; Dallas, Texas
Session Q7: System Biology III: The Physics of Evolution
11:15 AM–2:15 PM,
Wednesday, March 23, 2011
Room: Ballroom C3
Sponsoring Units: DBP DCP
Chair: Wouter Hoff, Oklahoma State University
Abstract ID: BAPS.2011.MAR.Q7.1
Abstract: Q7.00001 : Does Tumor Development Follow a Programmed Path?*
11:15 AM–11:51 AM
Preview Abstract Abstract
The initiation and progression of a tumor is a complex process, resembling the growth of a embryo in terms of the stages of development and increasing differentiation and somatic evolution of constituent cells in the community of cells that constitute the tumor. Typically we view cancer cells as rogue individuals violating the rules of the games played within an organism, but I would suggest that what we see is a programmed and algorithmic process. I will then question If tumor progression is dominated by the random acquisition of successive survival traits, or by a systematic and sequential unpacking of ``weapons'' from a pre-adapted ``toolkit'' of genetic and epigenetic potentialities? Can we then address this hypothesis by data mining solid tumors layer by layer?
*Support of the NSF and the NCI is gratefully acknowledged.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2011.MAR.Q7.1
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