Bulletin of the American Physical Society
APS March Meeting 2010
Volume 55, Number 2
Monday–Friday, March 15–19, 2010; Portland, Oregon
Session D10: Focus Session: Single Molecule Biophysics and Chemical Physics III
2:30 PM–5:30 PM,
Monday, March 15, 2010
Sponsoring Units: DCP DBP DPOLY
Chair: Rob Phillips, California Institute of Technology
Abstract ID: BAPS.2010.MAR.D10.4
Abstract: D10.00004 : Single-Molecule Investigations of Organic, Inorganic, and Organometallic Chemical Mechanisms*
3:30 PM–3:42 PM
Preview Abstract Abstract
(University of California, Irvine)
Single-molecule fluorescence microscopy has the potential to revolutionize the way in which chemical mechanisms are studied and chemical reactions are improved. Single-molecule techniques will reveal reactivity distributions, which are obscured by traditional ensemble spectroscopic techniques, and will determine active catalysts by direct observation. The potential of single-molecule fluorescence microscopy to address diverse chemical questions, however, has not yet been realized. Previous methods for imaging covalent bond formation were limited to studying chemical reactions that destroyed or produced a fluorophore. We developed a spectator fluorophore imaging technique that does not have this limitation, and which will be generalizable to a large number of chemical reactions, providing unprecedented detail into reaction mechanisms and processes. The formation of individual Pt-S and Pd-P covalent-bonds were imaged on supports similar to those employed in recyclable heterogeneous metal catalysts. A variation in the number of bond-forming events over small surface areas revealed the heterogeneity of the surface's binding properties, which was obscured by traditional ensemble spectroscopy techniques. The application of this technique to the study of broad problems in catalysis will be discussed.
*Supported by NSF (CAREER Award).
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2010.MAR.D10.4
The American Physical Society (APS) is a non-profit membership organization working to advance the knowledge of physics.
1 Physics Ellipse, College Park, MD 20740-3844
Editorial Office 1 Research Road, Ridge, NY 11961-2701 (631) 591-4000
Office of Public Affairs 529 14th St NW, Suite 1050, Washington, D.C. 20045-2001 (202) 662-8700