Session C1: Poster Session I: 2:00 pm - 5:00 pm
2:00 PM–2:00 PM, Monday, March 10, 2008
Morial Convention Center Room: Exhibit Hall A
Sponsoring Unit:
APS
Abstract ID: BAPS.2008.MAR.C1.258
Abstract: C1.00258 : An Empirical Study of Immune System Based On Bipartite Graphs
Preview Abstract
MathJax On | Off 
Abstract 
Authors:
Yu-Jing Peng
(Yangzhou University)
Sheng-Rong Zou
(Yangzhou University)
Zhong-Wei Guo
(Yangzhou University)
Ta Zhou
(Yangzhou University)
Chang-gui Gu
(Yangzhou University)
Da-Ren He
(Yangzhou University)
Immune system is the most important defense system to resist human pathogens. We present an immune bipartite graph model. Firstly we collect data through COPE database and then construct an immune cell-mediator network. In the net the immune cells can be regarded as collaboration acts and the mediators can be regarded as collaboration actors. The act degree distribution of this network is proved to be power-law with a scaling exponent 1.8. From our analysis, we found that some mediators with high degree are very important in the process of regulating immune activity, such as TNF-alpha, IL-8, TNF-alpha receptors, CCL5, IL-6, IL-2 receptors, TNF-beta receptors, TNF-beta, IL-4 receptors, IL-1 beta, CD54 and so on. We also found that the assortativity coefficient of the immune network is -0.27.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2008.MAR.C1.258