Session Y1: Engineering Biomolecules and Circuits by Rational Design and Genetic Selection

8:00 AM–11:00 AM, Friday, March 17, 2006
Baltimore Convention Center Room: Ballroom IV

Sponsoring Units: DCMP DBP
Chair: Andrea Liu, University of Pennsylvania

Abstract ID: BAPS.2006.MAR.Y1.1

Abstract: Y1.00001 : Molecular Evolution of Gene Expression in E. coli

8:00 AM–8:36 AM

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Author:

  Terry Hwa
    (University of California San Diego)

Understanding the evolution of gene regulation is an outstanding challenge to systems biology. Here we use molecular methods to study in detail the evolution of promoter sequences needed to express gene(s) essential to the growth of E. coli cells. We quantitatively characterize changes in the genotype and phenotype of the evolving population, and study how different challenges imposed by the environment affect the dynamics and the final outcome of the evolutionary process.

To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2006.MAR.Y1.1