Session G29: Focus Session: Physical and Engineering Constraints on the Function of Biological Systems

8:00 AM–11:00 AM, Tuesday, March 14, 2006
Baltimore Convention Center Room: 326

Sponsoring Unit: DBP
Chair: Partha Mitra, Cold Spring Harbor Laboratory

Abstract ID: BAPS.2006.MAR.G29.9

Abstract: G29.00009 : Radiation Damage From Mono-energetic Electrons Up to 200 keV On Biological Systems

10:24 AM–10:36 AM

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  Yuriy Prilepskiy
    (Hampton University)

The electron gun of the CEBAF machine at Jefferson lab (Newport News, VA) is capable of delivering electrons with energies up to 200 keV with a resolution of about 10$^{-5}$. This 1.5 GHz beam permits to generate cellular radiation damage within minutes. We have performed irradiation of cancer cells with different energies and different currents to investigate their biological responses. This study will permit to address the physical processes involved in the RBE and LET at a level that supersedes current data listed in the literature by orders of magnitude. We will discuss the experimental setup and results of the first stage of data collected with this novel system. This research is part of a global program to provide detailed information for the understanding of radiation based cancer treatments.

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