Session B13: Focus Session: Spectroscopy of Biomolecules from Isolated Molecules to Cell Environment II
11:15 AM–2:15 PM, Monday, March 13, 2006
Baltimore Convention Center Room: 305
Sponsoring Units: DCP DBP
Chair: Philip Anfinrud, National Institutes of Health
Abstract ID: BAPS.2006.MAR.B13.1
Abstract: B13.00001 : Structure and Interactions of Isolated Biomolecular Building Blocks.
11:15 AM–11:51 AM
Mattanjah de Vries
We investigate biomolecular building blocks and their clusters with each other and with water on a single molecular level. The motivation is the need to distinguish between intrinsic molecular properties and those that result from the biological environment. This is achieved by a combination of laser desorption and jet cooling, applied to aromatic amino acids, small peptides containing those, nucleobases and nucleosides. This approach is coupled with a number of laser spectroscopic techniques, including resonant multi-photon ionization, spectral hole burning and infra-red ion-dip spectroscopy. We will discuss examples illustrating how information can be obtained on spatial structure of individual biomolecules, including peptide conformations and details of DNA base-pairing.
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2006.MAR.B13.1