Bulletin of the American Physical Society
71st Annual Meeting of the APS Division of Fluid Dynamics
Volume 63, Number 13
Sunday–Tuesday, November 18–20, 2018; Atlanta, Georgia
Session G19: Biological fluid dynamics: Hearts and Lungs
10:35 AM–12:45 PM,
Monday, November 19, 2018
Georgia World Congress Center
Room: B306
Chair: Kenneth Kiger, University of Maryland, College Park
Abstract ID: BAPS.2018.DFD.G19.2
Abstract: G19.00002 : Tracking of virtual particles from volumetric velocity measurements: applications to physiological flows*
10:48 AM–11:01 AM
Presenter:
Omid Amili
(University of Minnesota, Twin Cities)
Authors:
Omid Amili
(University of Minnesota, Twin Cities)
Sean Moen
(University of Minnesota, Twin Cities)
Robroy MacIver
(Children's Hospitals and Clinics of MN)
Jafar Golzarian
(University of Minnesota, Twin Cities)
Filippo Coletti
(University of Minnesota, Twin Cities)
Continuous advancements in medical imaging are allowing the study of physiological flows with increasing accuracy and resolution, both in vitro and in vivo. In several biomedical settings, the transport of particles is an important aspect of the fluid dynamic problem, for example in the delivery of inhaled or injected drugs, and the fate of harmful agents through vessels and airways where such particles have often significant inertia. Here we utilize volumetric (three-dimensional, three-component) velocity fields obtained by Magnetic Resonance Velocimetry (MRV) to study the transport of inertial particles in cardiovascular and respiratory flows. We apply a well-established form of the particle equation of motion to track particles of given inertia that are virtually released in the flow which allows to calculate Lagrangian trajectories. The method is applied to a range of cases, including: blood clots from left ventricle assist device, thrombi in brain aneurysms, embolizing particles for tumor targeting, and inhaled aerosols in the bronchial tree.
*We acknowledge the support from the National Science Foundation (Chemical, Bioengineering, Environmental, and Transport Systems, grant 1453538) and the National Institutes of Health (grants NHLBI-R21HL129906 and 1S10OD017974-01).
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.DFD.G19.2
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