Bulletin of the American Physical Society
71st Annual Meeting of the APS Division of Fluid Dynamics
Volume 63, Number 13
Sunday–Tuesday, November 18–20, 2018; Atlanta, Georgia
Session D18: Medical Devices
2:30 PM–4:40 PM,
Sunday, November 18, 2018
Georgia World Congress Center
Room: B305
Chair: Jeremy Marston, Texas Tech University
Abstract ID: BAPS.2018.DFD.D18.6
Abstract: D18.00006 : In-vitro studies of jet injection dynamics*
3:35 PM–3:48 PM
Presenter:
FNU Pankaj
(Texas Tech Univ)
Authors:
FNU Pankaj
(Texas Tech Univ)
Jeremy O Marston
(Texas Tech Univ)
Recent advances in DNA-based vaccines require a precise drug delivery into intradermal and subcutaneous tissues, and drug manufacturers are increasingly seeking needle-free delivery methods, such as jet injection. In addition to jet speed and diameter, a key parameter that is thought to control deposition depth is the stand-off distance between the jet orifice and the skin.
In this talk, we will present some recent results from an in-vitro study on the dynamics of needle-free jet injection. The principle control parameter used in our study was the stand-off distance between the jet orifice and the target and we show that there is a counter-intuitive (nonlinear) relationship between the stand-off and the depth of injection. We also study the effect of fluid viscosity and target strength.
*Inovio Pharmaceuticals, NSF-CBET
To cite this abstract, use the following reference: http://meetings.aps.org/link/BAPS.2018.DFD.D18.6
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