Bulletin of the American Physical Society
APS April Meeting 2017
Volume 62, Number 1
Saturday–Tuesday, January 28–31, 2017; Washington, DC
Session B16: Applications of Accelerators and Nuclear PhysicsInvited
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Sponsoring Units: DNP DPB Chair: T Vincent Cianciolo, Oak Ridge National Laboratory Room: Washington 3 |
Saturday, January 28, 2017 10:45AM - 11:21AM |
B16.00001: Targeted Alpha Therapy: The US DOE Tri-Lab (ORNL, BNL, LANL) Research Effort to Provide Accelerator-Produced $^{\mathrm{\mathbf{225}}}$\textbf{Ac for Radiotherapy} Invited Speaker: Kevin John Targeted radiotherapy is an emerging discipline of cancer therapy that exploits the biochemical differences between normal cells and cancer cells to selectively deliver a lethal dose of radiation to cancer cells, while leaving healthy cells relatively unperturbed. A broad overview of targeted alpha therapy including isotope production methods, and associated isotope production facility needs, will be provided. A more general overview of the US Department of Energy Isotope Program's Tri-Lab (ORNL, BNL, LANL) Research Effort to Provide Accelerator-Produced $^{\mathrm{225}}$Ac for Radiotherapy will also be presented focusing on the accelerator-production of $^{\mathrm{225}}$Ac and final product isolation methodologies for medical applications. [Preview Abstract] |
Saturday, January 28, 2017 11:21AM - 11:57AM |
B16.00002: Particle Beam Therapy In The U.S. Invited Speaker: Jacek Capala The U.S. National Cancer Institute (NCI) has a long tradition of supporting research and development efforts in particle beam radiation therapy (PBRT) of cancer. Many preclinical studies investigating the effects of particle beams on tumor and normal tissues have been funded over the last five decades. In the 1970s and 1980s, NCI supported clinical trials using a variety of particle beams, many of them at the U.S. Department of Energy (DOE) facilities. Renewed interest in particle therapy led to a 2013 joint NCI/DOE workshop on particle RT-related R&D questions. Currently, clinical trials involving protons are being carried out by NCI-funded National Clinical Trials Network and under a collaborative agreement between NCI, MD Anderson Cancer Center, and Massachusetts General Hospital. To encourage establishment of a research center adjunct to a planned, independently created and funded clinical facility for PBRT, two exploratory project grants have been awarded. In addition, NCI has issued a contract to conduct a randomized phase III clinical trial of carbon ion vs. conventional (x-ray) RT for unresectable pancreatic cancer.\\ \\ Keywords: Cancer, Particle Beam Radiotherapy, Accelerators [Preview Abstract] |
Saturday, January 28, 2017 11:57AM - 12:33PM |
B16.00003: The Application of Neutron and X-Ray Techniques to Analyze Works of Art: Examples from The Unvarnished Truth Project Invited Speaker: Brandi Lee MacDonald When considered as an object, a painting consists of multiple components that, when analyzed together, have a unique story to tell about the artist, their practice, and the history of the work of art. Techniques traditionally applied in physics, including neutron-, x-radiographic and near-infrared imaging, and surface elemental analysis via x-ray fluorescence, are useful for generating significant insight into works of art. By examining the supporting material, grounds, pigments, and varnishes that a painter chose to utilize, we generate new knowledge regarding the composition, context, and decision-making involved in the creation of a work. The project `\textit{The Unvarnished Truth: exploring the material history of paintings'} is an interdisciplinary initiative that incorporated the expertise of forensic art historians, conservation scientists, physicists, and biomedical engineers. Through the technical analysis of nine paintings from the McMaster Museum of Art permanent collection, we explored research questions related to painting technique, attribution, authenticity, connoisseurship, and object condition and stability. The paintings span over 500 years of European art history, and include works from Vincent Van Gogh, Alexander Rodchenko, and A. van der Neer. This project highlights the multitude of ways in which micro- and non-destructive methods can be used to answer art historical questions. [Preview Abstract] |
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